Micro Plastics

What’s the relationship between microplastic exposure and diseases?

Health risk of human exposure to microplastics: a review ...

Recent studies suggest a strong correlation between microplastic (MP) exposure and various health conditions. It’s important to note that while research on the effects of MPs on human health is still emerging, evidence from animal and in vitro studies highlights potential health risks.  Key findings and potential mechanisms

  • Inflammation and gut health: MP exposure has been linked to inflammation and altered gut microbiota composition, a condition known as dysbiosis. This can lead to increased gut permeability, allowing harmful substances to enter the bloodstream and trigger systemic inflammation. Chronic inflammation is a significant risk factor for several diseases.
  • Cardiometabolic disorders: Research suggests a possible link between MPs and an increased risk of obesity, type 2 diabetes, and cardiovascular diseases. This may be due to the MPs interfering with insulin signaling and promoting inflammation in adipose (fat) tissue, accelerating aging processes in these tissues. A study found that patients with MPs in their arteries had a higher risk of heart attack, stroke, and death.
  • Neurotoxicity: MPs are increasingly linked to neuroinflammation and potential neurological and psychological disorders. Studies have shown that MPs can cross the blood-brain barrier and induce neurotoxicity through mechanisms like oxidative stress and altered neurotransmitter levels.
  • Reproductive health: Exposure to MPs has been associated with impaired male reproductive health, including reduced sperm quality, testicular inflammation, and hormonal imbalances. In females, MPs may disrupt the female reproductive system and negatively affect egg quality and fertility.
  • Cancer: Although direct links between MPs and cancer in humans are yet to be definitively proven, some studies in animal models and human cells suggest a potential association. MPs may induce oxidative stress and DNA damage, both known risk factors for cancer development. 

Need for further researchThe precise mechanisms by which MPs impact human health are still being investigated. More research, including long-term human studies and advanced methodologies, is crucial to fully understand the effects of MPs and develop strategies to mitigate their potential risks. In the meantime, experts recommend reducing exposure to plastics by making conscious choices in daily life, such as minimizing the use of single-use plastics and opting for alternatives like glass containers. 

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